GTX89310
NMDAR2B antibody, Internal
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX89310
- Zusätzliche Namen:
- glutamate ionotropic receptor NMDA type subunit 2B , EIEE27 , GluN2B , MRD6 , NMDAR2B , NR2B , NR3 , hNR3
- Anwendung:
- WB
- Konzentration:
- 0.50 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Rat
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Rat
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-KDAHEKDDFHHLS, from the internal region of the protein sequence according to NP_000825.1.
- Uniprot:
- Q13224
- Synonyme:
- DEE27;EIEE27;GluN2B;GluN2B(alt_5'UTR);glutamate [NMDA] receptor subunit epsilon-2;glutamate receptor ionotropic, NMDA 2B;glutamate receptor subunit epsilon-2;glutamate receptor, ionotropic, N-methyl D-aspartate 2B;hNR3;MRD6;N-methyl D-aspartate receptor subtype 2B;N-methyl-D-aspartate receptor subunit 3;NMDAR2B;NR2B;NR3
- Weitere Details:
- This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia. [provided by RefSeq, Aug 2017]
- Versandbedingungen:
- Blue Ice