GTX89303-PEP
NLRP3 (Internal) blocking peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX89303-PEP
- Zusätzliche Namen:
- Nlr Family Pyrin Domain Containing 3 , Agtavprl , Aii , Avp , C1Orf7 , Cias1 , Clr1.1 , Dfna34 , Fcas , Fcas1 , Fcu , Kefh , Mws , Nalp3 , Pypaf1 , Nlrp3
- Physischer Zustand:
- Lyophilized
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- NLR family, pyrin domain containing 3
- Spezies:
- Human
- Synonyme:
- AGTAVPRL;AII;AVP;C1orf7;caterpiller protein 1.1;CIAS1;CLR1.1;cold autoinflammatory syndrome 1 protein;cold-induced autoinflammatory syndrome 1 protein;cryopyrin;cryopyrin, NACHT, LRR and PYD domains - containing protein 3;deafness, autosomal dominant 34;DFNA34;FCAS;FCAS1;FCU;KEFH;MWS;NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3;NACHT, LRR and PYD containing protein 3;NACHT, LRR and PYD domains-containing protein 3;NALP3;nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3;PYPAF1;PYRIN-containing APAF1-like protein 1
- Weitere Details:
- This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data; however, insufficient evidence is available to determine if all of the represente
- Versandbedingungen:
- Blue Ice