GTX89278-PEP
FE65 blocking peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX89278-PEP
- Zusätzliche Namen:
- Amyloid Beta Precursor Protein Binding Family B Member 1 , Fe65 , Mgc:9072 , Rir , Apbb1
- Physischer Zustand:
- Lyophilized
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- amyloid beta precursor protein binding family B member 1
- Spezies:
- Human
- Synonyme:
- adaptor protein FE65a2;amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65);amyloid-beta A4 precursor protein-binding family B member 1;FE65;MGC:9072;RIR;stat-like protein
- Weitere Details:
- The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]
- Versandbedingungen:
- Blue Ice