GTX89257-PEP
Wilms Tumor 1 blocking peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX89257-PEP
- Zusätzliche Namen:
- Wilms Tumor 1 , Awt1 , Gud , Nphs4 , Wagr , Wit-2 , Wt33 , Wt1
- Physischer Zustand:
- Lyophilized
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- Wilms tumor 1
- Spezies:
- Human
- Synonyme:
- AWT1;GUD;NPHS4;WAGR;Wilms tumor 1;Wilms tumor protein;WIT-2;WT33
- Weitere Details:
- This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Oct 2010]
- Versandbedingungen:
- Blue Ice