NOD2 antibody, Internal

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX89233
Zusätzliche Namen:: nucleotide binding oligomerization domain containing 2 , ACUG , BLAU , BLAUS , CARD15 , CD , CLR16.3 , IBD1 , NLRC2 , NOD2B , PSORAS1 , YAOS
Anwendung:: WB
Konzentration:: 0.50 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Ammonium Sulfate Precipitated; Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Goat
Reaktivitäten:: Human
Buffer:: TBS, 0.5% BSA, 0.02% Sodium azide.
Immunogen:: Peptide with sequence KFRFTDRERHCSPTD, from the internal region of the protein sequence according to NP_071445.1.
Uniprot:: Q9HC29
Synonyme:: ACUG;BLAU;BLAUS;CARD15;caspase recruitment domain family, member 15;caspase recruitment domain protein 15;caspase recruitment domain-containing protein 15;CD;CLR16.3;IBD1;inflammatory bowel disease protein 1;NLR family, CARD domain containing 2;NLRC2;NOD-like receptor C2;NOD2B;nucleotide-binding oligomerization domain 2;nucleotide-binding oligomerization domain-containing protein 2;nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2;PSORAS1;YAOS
Weitere Details:: This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

Versandbedingungen:: Blue Ice