GTX89208
RNF213 antibody, Internal
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX89208
- Zusätzliche Namen:
- Ring Finger Protein 213 , Alo17 , C17Orf27 , Kiaa1618 , Mymy2 , Mystr , Net57 , Rnf213
- Anwendung:
- IHC-P
- Konzentration:
- 0.50 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-KNPQTQTEERFRPQ, from the internal region of the protein sequence according to NP_065965.3.
- Synonyme:
- ALK lymphoma oligomerization partner on chromosome 17;ALO17;C17orf27;E3 ubiquitin-protein ligase RNF213;KIAA1618;MYMY2;mysterin;MYSTR;NET57;RING-type E3 ubiquitin transferase RNF213
- Weitere Details:
- This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
- Versandbedingungen:
- Blue Ice