Cav beta 4 antibody, Internal

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX89203
Zusätzliche Namen:: calcium voltage-gated channel auxiliary subunit beta 4 , CAB4 , CACNLB4 , EA5 , EIG9 , EJM , EJM4 , EJM6
Anwendung:: WB
Konzentration:: 0.50 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Ammonium Sulfate Precipitated; Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Goat
Reaktivitäten:: Human
Buffer:: TBS, 0.5% BSA, 0.02% Sodium azide.
Immunogen:: Peptide with sequence C-DYPDSYQDTYKPH, from the internal region (near the C Terminus) of the protein sequence according to NP_001005747.1; NP_000717.2; NP_001005746.1.
Uniprot:: O00305
Synonyme:: CAB4;CACNLB4;calcium channel voltage-dependent subunit beta 4;dihydropyridine-sensitive L-type, calcium channel beta-4 subunit;EA5;EIG9;EJM;EJM4;EJM6;voltage-dependent L-type calcium channel subunit beta-4
Weitere Details:: This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE), juvenile myoclonic epilepsy (JME), and episodic ataxia, type 5. [provided by RefSeq, Aug 2016]

Versandbedingungen:: Blue Ice