GTX89019-PEP
DIO2 blocking peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX89019-PEP
- Zusätzliche Namen:
- Iodothyronine Deiodinase 2 , 5Dii , D2 , Dioii , Sely , Txdi2 , Dio2
- Physischer Zustand:
- Lyophilized
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- deiodinase, iodothyronine, type II
- Spezies:
- Human
- Synonyme:
- 5DII;D2;deiodinase-2;deiodinase, iodothyronine type II;deiodonase-2;DIOII;selenoprotein Y;SELENOY;SelY;thyroxine deiodinase, type II;TXDI2;type 2 DI;type 2 iodothyronine deiodinase;type II iodothyronine deiodinase;type-II 5'-deiodinase;type-II 5'deiodinase
- Weitere Details:
- The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice