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GTX88823-PEP

Pyruvate Carboxylase blocking peptide

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX88823-PEP
Zusätzliche Namen:
Pyruvate Carboxylase , Pcb , Pc
Physischer Zustand:
Lyophilized
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Buffer:
Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
Immunogen:
pyruvate carboxylase
Spezies:
Human
Synonyme:
PCB;pyruvate carboxylase, mitochondrial;pyruvic carboxylase
Weitere Details:
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
Versandbedingungen:
Blue Ice