GTX88773-PEP
DUOX1 blocking peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX88773-PEP
- Zusätzliche Namen:
- Dual Oxidase 1 , Lnox1 , Noxef1 , Thox1 , Duox1
- Physischer Zustand:
- Lyophilized
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- dual oxidase 1
- Spezies:
- Human
- Synonyme:
- dual oxidase 1;flavoprotein NADPH oxidase;large NOX 1;LNOX1;long NOX 1;NADPH thyroid oxidase 1;nicotinamide adenine dinucleotide phosphate oxidase;NOXEF1;THOX1;thyroid oxidase 1
- Weitere Details:
- The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2012]
- Versandbedingungen:
- Blue Ice