GTX88681
OTUB1 antibody, Internal
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX88681
- Zusätzliche Namen:
- OTU deubiquitinase, ubiquitin aldehyde binding 1 , HSPC263 , OTB1 , OTU1
- Anwendung:
- WB
- Konzentration:
- 0.50 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Mouse
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Mouse
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-YKEYAEDDNIYQQK, from the internal region of the protein sequence according to NP_060140.2.
- Uniprot:
- Q96FW1
- Synonyme:
- deubiquitinating enzyme OTUB1;HSPC263;OTB1;OTU domain-containing ubiquitin aldehyde-binding protein 1;OTU domain, ubiquitin aldehyde binding 1;OTU-domain Ubal-binding 1;OTU1;otubain-1;ubiquitin thioesterase OTUB1;ubiquitin-specific protease otubain 1;ubiquitin-specific-processing protease OTUB1
- Weitere Details:
- The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice