GTX88640
ABHD12 antibody, C-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX88640
- Zusätzliche Namen:
- abhydrolase domain containing 12 , ABHD12A , BEM46L2 , C20orf22 , PHARC , dJ965G21.2
- Anwendung:
- WB
- Konzentration:
- 0.50 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Mouse
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-REFLGKSEPEHQH, from the C Terminus of the protein sequence according to NP_001035937.1; NP_056415.1.
- Uniprot:
- Q8N2K0
- Synonyme:
- 2-arachidonoylglycerol hydrolase;2-arachidonoylglycerol hydrolase ABHD12;ABHD12A;abhydrolase domain-containing protein 12;BEM46L2;C20orf22;dJ965G21.2;hABHD12;lysophosphatidylserine lipase ABHD12;monoacylglycerol lipase ABHD12;oxidized phosphatidylserine lipase ABHD12;PHARC
- Weitere Details:
- This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011]
- Versandbedingungen:
- Blue Ice