SUR1 blocking peptide

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX88616-PEP
Zusätzliche Namen:: Atp Binding Cassette Subfamily C Member 8 , Abc36 , Hhf1 , Hi , Hrins , Mrp8 , Phhi , Sur , Sur1 , Sur1Delta2 , Tndm2 , Abcc8
Physischer Zustand:: Lyophilized
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Buffer:: Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
Immunogen:: ATP binding cassette subfamily C member 8
Spezies:: Human
Synonyme:: ABC36;ATP-binding cassette sub-family C member 8;ATP-binding cassette transporter sub-family C member 8;ATP-binding cassette, sub-family C (CFTR/MRP), member 8;HHF1;HI;HRINS;MRP8;PHHI;PNDM3;sulfonylurea receptor (hyperinsulinemia);sulfonylurea receptor 1;SUR;SUR1;SUR1delta2;TNDM2
Weitere Details:: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed; however, the transcript variants have not been fully described. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice