GTX88611
PTPRN antibody, Internal
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX88611
- Zusätzliche Namen:
- protein tyrosine phosphatase receptor type N , IA-2 , IA-2/PTP , IA2 , ICA512 , R-PTP-N
- Anwendung:
- WB
- Konzentration:
- 0.50 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Mouse
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Mouse
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-QGEGNIKKNRHPD, from the internal region of the protein sequence according to NP_002837.1.
- Uniprot:
- Q16849
- Synonyme:
- IA-2;IA-2/PTP;IA2;ICA 512;ICA512;insulinoma-associated tyrosine-phosphatase-like protein;islet cell antigen 2;islet cell antigen 512;islet cell autoantigen 3;protein tyrosine phosphatase-like N;PTP IA-2;R-PTP-N;receptor-type tyrosine-protein phosphatase-like N
- Weitere Details:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
- Versandbedingungen:
- Blue Ice