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GTX88492-PEP

GAD67 blocking peptide

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX88492-PEP
Zusätzliche Namen:
Glutamate Decarboxylase 1 , Cpsq1 , Gad , Scp , Gad1
Physischer Zustand:
Lyophilized
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Buffer:
Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
Immunogen:
glutamate decarboxylase 1
Spezies:
Human
Synonyme:
67 kDa glutamic acid decarboxylase;CPSQ1;DEE89;GAD;GAD-67;glutamate decarboxylase 1;glutamate decarboxylase 1 (brain, 67kDa);SCP
Weitere Details:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
Versandbedingungen:
Blue Ice