GTX88466
ITM2B antibody, Internal
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX88466
- Zusätzliche Namen:
- integral membrane protein 2B , ABRI , BRI , BRI2 , BRICD2B , E25B , E3-16 , FBD , RDGCA , imBRI2
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.50 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-HDKETYKLQRRETIK, from the internal region of the protein sequence according to NP_068839.1.
- Uniprot:
- Q9Y287
- Synonyme:
- ABRI;ABri/ADan amyloid peptide;BRI;BRI2;BRICD2B;BRICHOS domain containing 2B;E25B;E3-16;epididymis secretory sperm binding protein;FBD;imBRI2;immature BRI2;integral membrane protein 2B;Protein E25B;RDGCA;transmembrane protein BRI
- Weitere Details:
- Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq, Oct 2009]
- Versandbedingungen:
- Blue Ice