GTX88319
Desmoglein 1 antibody, Internal
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX88319
- Zusätzliche Namen:
- desmoglein 1 , CDHF4 , DG1 , DSG , EPKHE , EPKHIA , PPKS1 , SPPK1
- Anwendung:
- IHC-P
- Konzentration:
- 0.50 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-YTTSDTLKPSVHVHD, from the internal region of the protein sequence according to NP_001933.2.
- Uniprot:
- Q02413
- Synonyme:
- cadherin family member 4;CDHF4;desmoglein-1;desmosomal glycoprotein 1;DG1;DSG;EPKHE;EPKHIA;pemphigus foliaceus antigen;PPKS1;SPPK1
- Weitere Details:
- This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]
- Versandbedingungen:
- Blue Ice