GTX88191
EVI1 antibody, Internal
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX88191
- Zusätzliche Namen:
- Mds1 And Evi1 Complex Locus , Aml1-Evi-1 , Evi1 , Kmt8E , Mds1 , Mds1-Evi1 , Prdm3 , Rusat2 , Mecom
- Anwendung:
- WB
- Konzentration:
- 0.50 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-DKESLHSTSH, from the internal region of the protein sequence according to NP_001098547.3; NP_005232.2; NP_004982.2; NP_001157471.1; NP_001157472.1.
- Synonyme:
- AML1-EVI-1;AML1-EVI-1 fusion protein;ecotropic virus integration site 1 protein homolog;EVI1;histone-lysine N-methyltransferase MECOM;KMT8E;MDS1;MDS1 and EVI1 complex locus protein EVI1;MDS1 and EVI1 complex locus protein MDS1;MDS1-EVI1;myelodysplasia syndrome-associated protein 1;oncogene EVI1;PR domain 3;PRDM3;RUSAT2;zinc finger protein Evi1
- Weitere Details:
- The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
- Versandbedingungen:
- Blue Ice