GTX88141
LAIR1 antibody, Internal
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX88141
- Zusätzliche Namen:
- leukocyte associated immunoglobulin like receptor 1 , CD305 , LAIR-1
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.50 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-NDTEDVSQASPSE, from the internal region of the protein sequence according to NP_002278.1; NP_068352.1.
- Uniprot:
- Q6GTX8
- Synonyme:
- CD305;immunoglobulin heavy chain variable region;LAIR-1;leukocyte-associated Ig-like receptor 1;leukocyte-associated immunoglobulin-like receptor 1
- Weitere Details:
- The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
- Versandbedingungen:
- Blue Ice