GTX88103-PEP
IL12 Receptor beta1 blocking peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX88103-PEP
- Zusätzliche Namen:
- Interleukin 12 Receptor Subunit Beta 1 , Cd212 , Il-12R-Beta1 , Il12Rb , Imd30 , Il12Rb1
- Physischer Zustand:
- Lyophilized
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- interleukin 12 receptor subunit beta 1
- Spezies:
- Human
- Synonyme:
- CD212;cluster of differentiation 212;IL-12 receptor beta component;IL-12 receptor subunit beta-1;IL-12R subunit beta-1;IL-12R-BETA1;IL12RB;IMD30;interleukin 12 receptor, beta 1;interleukin-12 receptor beta-1 chain;interleukin-12 receptor subunit beta-1
- Weitere Details:
- The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
- Versandbedingungen:
- Blue Ice