PBX1 blocking peptide

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX88088-PEP
Zusätzliche Namen:: Pbx Homeobox 1 , Cakuhed , Pbx1
Physischer Zustand:: Lyophilized
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Buffer:: Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
Immunogen:: pre-B-cell leukemia homeobox 1
Spezies:: Human
Synonyme:: CAKUHED;homeobox protein PBX1;homeobox protein PRL;pre-B-cell leukemia homeobox 1;pre-B-cell leukemia transcription factor 1
Weitere Details:: This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]