GTX87948
MED23 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX87948
- Zusätzliche Namen:
- ARC130 , CRSP130 , CRSP133 , CRSP3 , DRIP130 , MED23 , MRT18 , SUR2 , mediator complex subunit 23
- Anwendung:
- IHC-P, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human MED23 (1-50).
- Uniprot:
- Q9ULK4
- Synonyme:
- 130 kDa transcriptional co-activator;133 kDa transcriptional co-activator;activator-recruited cofactor 130 kDa component;ARC130;cofactor required for Sp1 transcriptional activation subunit 3;CRSP130;CRSP133;CRSP3;DRIP130;Mediator complex subunit 23;mediator of RNA polymerase II transcription subunit 23;mental retardation, non-syndromic, autosomal recessive, 18;MRT18;Protein sur-2 homolog;SUR-2;SUR2;Transcriptional coactivator CRSP130;vitamin D3 receptor interacting protein;Vitamin D3 receptor-interacting protein complex 130 kDa component
- Weitere Details:
- The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012]
- Versandbedingungen:
- Blue Ice