GTX87772
ATF6B antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX87772
- Zusätzliche Namen:
- ATF6B , CREBL1 , CREBRP , G13 , activating transcription factor 6 beta
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human ATF6B (401-450).
- Uniprot:
- Q99941
- Synonyme:
- Activating transcription factor 6 beta;cAMP response element-binding protein-related protein;cAMP-dependent transcription factor ATF-6 beta;cAMP-responsive element-binding protein-like 1;Creb-related protein;CREB-RP;CREBL1;cyclic AMP-dependent transcription factor ATF-6 beta;G13;protein G13
- Weitere Details:
- The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
- Versandbedingungen:
- Blue Ice