GTX87162
IL7 Receptor alpha antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX87162
- Zusätzliche Namen:
- CD127 , CDW127 , IL7R , IL7RA , IL7Ralpha , ILRA , interleukin 7 receptor , IL7-R alpha
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human IL7 Receptor alpha (410-459).
- Uniprot:
- P16871
- Synonyme:
- CD127;CD127 antigen;CDW127;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL7RA;ILRA;interleukin 7 receptor alpha chain;interleukin-7 receptor subunit alpha
- Weitere Details:
- The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2014]
- Versandbedingungen:
- Blue Ice