GTX87124
MED14 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX87124
- Zusätzliche Namen:
- CRSP150 , CRSP2 , CSRP , CXorf4 , DRIP150 , EXLM1 , MED14 , RGR1 , TRAP170 , mediator complex subunit 14
- Anwendung:
- IHC-P, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human MED14 (701-750).
- Uniprot:
- O60244
- Synonyme:
- activator-recruited cofactor 150 kDa component;ARC150;Cofactor required for Sp1 transcriptional activation subunit 2;cofactor required for Sp1 transcriptional activation, subunit 2 (150kD);CRSP complex subunit 2;CRSP150;CRSP2;CSRP;CXorf4;DRIP150;EXLM1;hRGR1;human homolog of yeast RGR1;Mediator complex subunit 14;mediator of RNA polymerase II transcription subunit 14;RGR1;RGR1 homolog;thyroid hormone receptor-associated protein complex 170 kDa component;thyroid hormone receptor-associated protein complex component TRAP170;transcriptional co-activator CRSP150;Transcriptional coactivator CRSP150;TRAP170;vitamin D receptor-interacting protein complex component DRIP150;vitamin D3 receptor-interacting protein complex 150 kDa component
- Weitere Details:
- The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice