GTX86983
MBTPS2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX86983
- Zusätzliche Namen:
- BRESEK , IFAP , KFSD , KFSDX , MBTPS2 , OLMSX , S2P , membrane bound transcription factor peptidase, site 2
- Anwendung:
- IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human MBTPS2 (301-350).
- Uniprot:
- O43462
- Synonyme:
- BRESEK;endopeptidase S2P;IFAP;keratosis follicularis spinulosa decalvans;KFSD;KFSDX;membrane-bound transcription factor protease, site 2;membrane-bound transcription factor site-2 protease;OI19;OLMSX;S2P;site-2 protease;SREBPs intramembrane protease;sterol regulatory element-binding proteins intramembrane protease
- Weitere Details:
- This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009]
- Versandbedingungen:
- Blue Ice