GTX86982
ORCTL2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX86982
- Zusätzliche Namen:
- BWR1A , BWSCR1A , HET , IMPT1 , ITM , ORCTL2 , SLC22A18 , SLC22A1L , TSSC5 , p45BWR1A , solute carrier family 22 member 18
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human ORCTL2 (359-408).
- Uniprot:
- Q96BI1
- Synonyme:
- beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein;BWR1A;BWSCR1A;efflux transporter-like protein;HET;imprinted multi-membrane-spanning polyspecific transporter-related protein 1;IMPT1;ITM;ORCTL2;organic cation transporter-like protein 2;p45 Beckwith-Wiedemann region 1A;p45-Beckwith-Wiedemann region 1 A;p45-BWR1A;SLC22A1L;Solute carrier family 22 member 1-like;solute carrier family 22 member 18;TSSC5;tumor-suppressing STF cDNA 5 protein;tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein
- Weitere Details:
- This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms' tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Several alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2015]
- Versandbedingungen:
- Blue Ice