GTX85891
CDH13 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85891
- Zusätzliche Namen:
- cadherin 13 , CDH13 , CDHH , P105 , T-Cadherin , H-Cadherin , Cadherin 13
- Anwendung:
- ELISA, WB, IHC-P, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- A 15 amino acid synthetic peptide near the N-terminus of human T-cadherin. The immunogen is located within amino acids 150 - 200 of T-cadherin.
- Uniprot:
- P55290
- Synonyme:
- cadherin 13, H-cadherin (heart);cadherin-13;CDHH;H-cadherin (heart);heart cadherin;P105;T-cad;T-cadherin;Truncated cadherin
- Weitere Details:
- This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011]
- Versandbedingungen:
- Blue Ice