GTX85520
PERP antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85520
- Zusätzliche Namen:
- PERP, TP53 apoptosis effector , 1110017A08Rik , KCP1 , KRTCAP1 , PIGPC1 , THW
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- PERP antibody was raised against a synthetic peptide corresponding to 17 amino acids near the carboxy terminus of human PERP.The immunogen is located within the last 50 amino acids of PERP.
- Uniprot:
- Q9JK95
- Synonyme:
- 1110017A08Rik;KCP;KCP-1;KCP1;keratinocyte-associated protein 1;KRTC;KRTCAP1;p53 apoptosis effector related to PMP-22;p53 apoptosis effector related to Pmp22;p53 apoptosis-associated target;PIG;PIGPC1;THW
- Weitere Details:
- The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2 , p53R2 (2), p53AIP1 (3), Noxa (4), PIDD (5), PID/MTA2 (6), MTBP (7) and PERP (8), were identified and their genes were cloned recently. PERP, also termed PIGPC1 and THW, is a plasma membrane protein (8-10). p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis (8). The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family (8).
- Versandbedingungen:
- Blue Ice