GTX85519
TTC5 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85519
- Zusätzliche Namen:
- tetratricopeptide repeat domain 5 , Strap
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- TTC5 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human TTC5.The immunogen is located within the last 50 amino acids of TTC5.
- Uniprot:
- Q8N0Z6
- Synonyme:
- NEDCAFD;Strap;stress-responsive activator of p300;tetratricopeptide repeat protein 5;TPR repeat protein 5
- Weitere Details:
- Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats (1). Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 (2) and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5 (3), suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.
- Versandbedingungen:
- Blue Ice