GTX85490
IRF7 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85490
- Zusätzliche Namen:
- interferon regulatory factor 7 , IMD39 , IRF-7 , IRF-7H , IRF7A , IRF7B , IRF7C , IRF7H
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- IRF7 antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human IRF7.The immunogen is located within amino acids 420 - 470 of IRF7.
- Uniprot:
- Q92985
- Synonyme:
- IMD39;interferon regulatory factor 7;interferon regulatory factor-7H;IRF-7;IRF-7H;IRF7A;IRF7B;IRF7C;IRF7H
- Weitere Details:
- Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established.
- Versandbedingungen:
- Blue Ice