GTX85486
RPA Interacting Protein antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85486
- Zusätzliche Namen:
- RPA interacting protein , HRIP , RIP
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- RPA Interacting Protein antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human RPA Interacting Protein.The immunogen is located within the last 50 amino acids of RPA Interacting Protein.
- Uniprot:
- Q86UA6
- Synonyme:
- HRIP;nuclear transporter;RAP interaction protein;RIP;RPA-interacting protein
- Weitere Details:
- Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.
- Versandbedingungen:
- Blue Ice