Choline Acetyltransferase antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX85450
Zusätzliche Namen:: choline O-acetyltransferase , CHOACTASE , CMS1A , CMS1A2 , CMS6
Anwendung:: IHC, IHC-P, IF, ICC
Konzentration:: 100 ug/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Lagerbedingungen:: 2-8[o]C Do not freeze.
Hersteller:: Genetex
Host:: Chicken/Avian
Reaktivitäten:: Human, Mouse, Rat
Buffer:: PBS, 0.02% Sodium azide.
Immunogen:: Chickens were immunized with a synthetic peptide / keyhole limpet hemocyanin (KLH) conjugate. The peptide corresponded to a region of the Choline Acetyltransferase gene product shared between the human (P28329, NCBI) and mouse (Q03059, NCBI) sequences.
Uniprot:: P28329
Synonyme:: acetyl CoA:choline O-acetyltransferase;CHOACTASE;choline acetylase;choline O-acetyltransferase;CMS1A;CMS1A2;CMS6
Weitere Details:: This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010]