GTX85443
ORAI2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85443
- Zusätzliche Namen:
- ORAI calcium release-activated calcium modulator 2 , C7orf19 , CBCIP2 , MEM142B , TMEM142B
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- ORAI2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human ORAI2.The immunogen is located within the last 50 amino acids of ORAI2.
- Uniprot:
- Q96SN7
- Synonyme:
- C7orf19;CAP-binding protein complex interacting protein 2;CAP-binding protein complex-interacting protein 2;CBCIP2;H_NH0514P08.8;MEM142B;protein orai-2;putative protein ORAI2-2;TMEM142B;transmembrane protein 142B
- Weitere Details:
- Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1. This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI3.
- Versandbedingungen:
- Blue Ice