GTX85434
STEAP3 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85434
- Zusätzliche Namen:
- STEAP3 metalloreductase , AHMIO2 , STMP3 , TSAP6 , dudlin-2 , dudulin-2 , pHyde
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- STEAP3 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human STEAP3.The immunogen is located within the first 50 amino acids of STEAP3.
- Uniprot:
- Q658P3
- Synonyme:
- AHMIO2;dudlin-2;dudulin-2;metalloreductase STEAP3;pHyde;six-transmembrane epithelial antigen of prostate 3;STEAP family member 3, metalloreductase;STMP3;TSAP6;tumor suppressor pHyde;tumor suppressor-activated pathway protein 6
- Weitere Details:
- The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells. This STEAP3 antibody does not cross-react with other STEAP proteins.
- Versandbedingungen:
- Blue Ice