GTX85409
LGI2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85409
- Zusätzliche Namen:
- leucine-rich repeat LGI family, member 2 , mKIAA1916
- Anwendung:
- ELISA, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- LGI2 antibody was raised against a 11 amino acid synthetic peptide from near the amino terminus of human LGI2.The immunogen is located within the first 50 amino acids of LGI2.
- Uniprot:
- Q8K4Z0
- Synonyme:
- leucine-rich glioma-inactivated protein 2;leucine-rich repeat LGI family member 2;mKIAA1916
- Weitere Details:
- The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE. Three isoforms of LGI2 are known to exist; this LGI2 antibody will recognize only the longest. This LGI2 antibody is predicted to be specific to LGI2 and not recognize other LGI proteins.
- Versandbedingungen:
- Blue Ice