GTX85403
ELOVL6 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85403
- Zusätzliche Namen:
- ELOVL fatty acid elongase 6 , FACE , FAE , LCE
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- ELOVL6 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of the human ELOVL6.The immunogen is located within the first 50 amino acids of ELOVL6.
- Uniprot:
- Q9H5J4
- Synonyme:
- 3-keto acyl-CoA synthase ELOVL6;elongation of very long chain fatty acids protein 6;ELOVL FA elongase 6;ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast);ELOVL fatty acid elongase 6;FACE;FAE;fatty acid elongase 2;fatty acyl-CoA elongase;hELO2;LCE;long-chain fatty-acyl elongase;very long chain 3-ketoacyl-CoA synthase 6;very long chain 3-oxoacyl-CoA synthase 6
- Weitere Details:
- Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.
- Versandbedingungen:
- Blue Ice