GTX85343
LRFN3 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85343
- Zusätzliche Namen:
- leucine rich repeat and fibronectin type III domain containing 3 , FIGLER1 , SALM4
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- LRFN3 antibody was raised against a 16 amino acid synthetic peptide near the center of human LRFN3.The immunogen is located within amino acids 380 - 430 of LRFN3.
- Uniprot:
- Q9BTN0
- Synonyme:
- fibronectin type III, immunoglobulin and leucine rich repeat domains 1;FIGLER1;leucine-rich repeat and fibronectin type-III domain-containing protein 3;SALM4;synaptic adhesion-like molecule 4
- Weitere Details:
- LRFN3 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. This antibody is predicted to not cross-react with other members of the LRFN family.
- Versandbedingungen:
- Blue Ice