GTX85342
PCDH12 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85342
- Zusätzliche Namen:
- protocadherin 12 , VE-cadherin-2 , VECAD2
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- PCDH12 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human PCDH12.The immunogen is located within amino acids 30 - 80 of PCDH12.
- Uniprot:
- Q9NPG4
- Synonyme:
- DMJDS1;protocadherin-12;vascular cadherin-2;vascular endothelial cadherin 2;Vascular endothelial cadherin-2;VE-cad-2;VE-cadherin 2;VE-cadherin-2;VECAD2
- Weitere Details:
- Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA; further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12- mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2,289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling. This antibody is predicted to not cross-react with PCDH18.
- Versandbedingungen:
- Blue Ice