GTX85268
CCDC134 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85268
- Zusätzliche Namen:
- coiled-coil domain containing 134
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- CCDC134 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human CCDC134.The immunogen is located within the first 50 amino acids of CCDC134.
- Uniprot:
- Q9H6E4
- Synonyme:
- coiled-coil domain-containing protein 134
- Weitere Details:
- The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.
- Versandbedingungen:
- Blue Ice