GTX85265
MAK10 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85265
- Zusätzliche Namen:
- N(alpha)-acetyltransferase 35, NatC auxiliary subunit , EGAP , MAK10 , MAK10P , bA379P1.1
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- MAK10 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human MAK10.The immunogen is located within amino acids 190 - 240 of MAK10.
- Uniprot:
- Q5VZE5
- Synonyme:
- bA379P1.1;corneal wound healing-related protein;EGAP;embryonic growth-associated protein homolog;MAK10;MAK10 homolog, amino-acid N-acetyltransferase subunit;MAK10P;N-alpha-acetyltransferase 35, NatC auxiliary subunit;protein MAK10 homolog
- Weitere Details:
- The MAK10 gene encodes a 733-amino acid protein with several regions of similarity to T cell receptor alpha-subunit V (variable) regions in yeast. The mammalian homologue of yeast MAK10, also known as EGAP, is one subunit of a novel N-terminal acetyltransferase (NAT) that is highly conserved among vertebrate species. It is expressed in a variety of tissues in the developing rat embryo but restricted in expression in the adult, remaining detectable only in tissues undergoing continual cell renewal or in cells responding to pathological injury. The MAK10-NAT complex is an essential regulatory enzyme controlling the function of a subset of proteins required for embryonic growth control and vessel development. This complex functionally co-assembles in mammalian cells to regulate cell proliferation and is essential for embryonic development, at least in part through the regulation of target of rapamycin (TOR) signaling events. At least two isoforms of MAK10 are known to exist.
- Versandbedingungen:
- Blue Ice