GTX85208
ARHGAP18 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85208
- Zusätzliche Namen:
- Rho GTPase activating protein 18 , MacGAP , SENEX , bA307O14.2
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- ARHGAP18 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ARHGAP18.The immunogen is located within the last 50 amino acids of ARHGAP18.
- Uniprot:
- Q8N392
- Synonyme:
- bA307O14.2;MacGAP;rho GTPase-activating protein 18;rho-type GTPase-activating protein 18;SENEX
- Weitere Details:
- ARHGAP18 is one member of the human RhoGAP family with approximately 80 RhoGAP proteins known to be encoded in the human genome. Rho proteins belong to the Ras superfamily that is composed of over 50 members divided into six families, including Ras, Sar, Rho, Ran, Rab and Arf. Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. ARHGAP18 is linked to Ras, and thus, to EGFR-mediated proliferation, migration and differentiation. ARHGAP18 is precisely contained within chromosome 6q22-24, which has been shown to be linked to schizophrenia, suggesting that ARHGEP18 may play a role in this condition.
- Versandbedingungen:
- Blue Ice