GTX85198
Slc37A2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85198
- Zusätzliche Namen:
- solute carrier family 37 member 2 , pp11662
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Slc37A2 antibody was raised against a 15 amino acid synthetic peptide near the center of human Slc37A2.The immunogen is located within amino acids 230 - 280 of Slc37A2(Accession # NP_938018).
- Uniprot:
- Q8TED4
- Synonyme:
- glucose-6-phosphate exchanger SLC37A2;pp11662;solute carrier family 37 (glucose-6-phosphate transporter), member 2;solute carrier family 37 (glycerol-3-phosphate transporter), member 2;Solute carrier family 37 member 2;SPX2;sugar phosphate exchanger 2
- Weitere Details:
- The Slc37 gene family consists of four members which have 10-12 predicted transmembrane domains and belong to the sugar-phosphate transporter superfamily. Recent experiments have demonstrated that Slc37A2 is a macrophage-specific gene selectively expressed in obese white adipose tissue. Its transcript is also expressed in spleen and thymus and the cell lines RAW264.7 and THP-1. Compared to wild-type mice, Slc37A2 mRNA is expressed at nine-fold higher levels in abdominal epididymal fat deposits of ob/ob mice, suggesting that it may be required to limit the contribution of macrophages to the inflammatory state present in obesity. Slc37A2 protein is post-translationally modified with the addition of N-linked glycans and migrates as a heterogeneous species of 50-75kDa.
- Versandbedingungen:
- Blue Ice