GTX85174
SCUBE1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85174
- Zusätzliche Namen:
- signal peptide, CUB domain and EGF like domain containing 1
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- SCUBE1 antibody was raised against a 14 amino acid synthetic peptide near the center of human SCUBE1.The immunogen is located within amino acids 460 - 510 of SCUBE1.
- Uniprot:
- Q8IWY4
- Synonyme:
- signal peptide-CUB domain-EGF-related 1;signal peptide, CUB and EGF-like domain-containing protein 1;signal peptide, CUB domain, EGF-like 1
- Weitere Details:
- SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity; genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.
- Versandbedingungen:
- Blue Ice