GTX85173
SCUBE2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85173
- Zusätzliche Namen:
- signal peptide, CUB domain and EGF like domain containing 2 , CEGB1 , CEGF1 , CEGP1 , scube/You
- Anwendung:
- ELISA, Flow Cytometry, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- SCUBE2 antibody was raised against a 17 amino acid synthetic peptide near the center of human SCUBE2.The immunogen is located within amino acids 480 - 530 of SCUBE2.
- Uniprot:
- Q9NQ36
- Synonyme:
- CEGB1;CEGF1;CEGP1;Protein CEGP1;scube/You;signal peptide, CUB and EGF-like domain-containing protein 2
- Weitere Details:
- SCUBE2 is a member of a family of secreted glycoproteins that contain N-terminal EGF-like repeats and C-terminal cysteine-rich motifs and CUB domain and are expressed in embryonic neuroectoderm and vascular epithelium. SCUBE2 is a close homolog to SCUBE1 and can form a heterodimeric complex with SCUBE1. SCUBE2 is thought to participate in the Hedgehog signaling pathway by specifically interacting with Sonic Hedgehog (SHH) and the receptor PTCH1, enhancing the SHH signaling activity in the raft microdomains of the plasma membrane, and may thus play important roles in organ development and tumor progression.
- Versandbedingungen:
- Blue Ice