GTX85169
CaBP7 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85169
- Zusätzliche Namen:
- calcium binding protein 7 , CALN2
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- CaBP7 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human CaBP7.The immunogen is located within the first 50 amino acids of CaBP7.
- Uniprot:
- Q86V35
- Synonyme:
- calcium-binding protein 7;CALN2;calneuron 2;calneuron II;Calneuron-2
- Weitere Details:
- Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP7 (Calcium-binding protein 7), contains two EF-hand domains for calcium binding and shares 70% homology with CaBP8 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.
- Versandbedingungen:
- Blue Ice