GTX85167
CCDC106 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85167
- Zusätzliche Namen:
- coiled-coil domain containing 106 , HSU79303 , ZNF581
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- CCDC106 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human CCDC106.The immunogen is located within the last 50 amino acids of CCDC106.
- Uniprot:
- Q9BWC9
- Synonyme:
- coiled-coil domain-containing protein 106;HSU79303;protein predicted by clone 23882;ZNF581
- Weitere Details:
- The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.
- Versandbedingungen:
- Blue Ice