GTX85158
NALP5 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85158
- Zusätzliche Namen:
- NLR family pyrin domain containing 5 , CLR19.8 , MATER , NALP5 , PAN11 , PYPAF8
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- NALP5 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human NALP5.The immunogen is located within the last 50 amino acids of NALP5.
- Uniprot:
- P59047
- Synonyme:
- CLR19.8;MATER;mater protein homolog;maternal antigen that embryos require;NACHT, leucine rich repeat and PYD containing 5;NACHT, LRR and PYD domains-containing protein 5;NALP5;nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5;PAN11;PYPAF8
- Weitere Details:
- NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.
- Versandbedingungen:
- Blue Ice