GTX85157
NALP6 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85157
- Zusätzliche Namen:
- NLR family pyrin domain containing 6 , AVR , CLR11.4 , NALP6 , NAVR , NAVR/AVR , PAN3 , PYPAF5
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- NALP6 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP6.The immunogen is located within amino acids 150 - 200 of NALP6.
- Uniprot:
- P59044
- Synonyme:
- angiotensin II/vasopressin receptor;AVR;CLR11.4;NACHT, leucine rich repeat and PYD containing 6;NACHT, LRR and PYD domains-containing protein 6;NALP6;NAVR;NAVR/AVR;nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 6;PAN3;PYPAF5;PYRIN-containing APAF1-like protein 5
- Weitere Details:
- NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC. Co-expression of NALP6 with ASC results in a synergistic activation of NF-kB and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals.
- Versandbedingungen:
- Blue Ice