GTX85151
PLAC1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85151
- Zusätzliche Namen:
- placenta enriched 1 , CT92 , OOSP2B , OOSP2L
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- PLAC1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human PLAC1.The immunogen is located within amino acids 130 - 180 of PLAC1.
- Uniprot:
- Q9HBJ0
- Synonyme:
- cancer/testis antigen 92;CT92;OOSP2B;OOSP2L;placenta specific 1;placenta-specific protein 1
- Weitere Details:
- PLAC1 was initially identified as a protein expressed specifically in the placenta and other cells derived from the trophoblast lineage during embryonic development, but has also been found to be expressed ectopically in a wide range of human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein that is thought to serve a receptor-like function modulating cell-cell or ligand receptor interactions unique to the maternal-placental interface. Decreased expression of PLAC1 is associated with decreased expression of cyclin D1 and reduced expression of AKT kinase, which, combined with the fact that PLAC1 is expressed on the surface of cancer cells, suggests that PLAC1 may be an effective candidate for immunotherapeutic treatments of cancer.
- Versandbedingungen:
- Blue Ice